First Nano Particle-Based Surgical Adhesive to be Visible When Viewed Using Medical Imaging Techniques

Posted on 8/22/2017 8:40:45 AM By ASC

Surgical adhesives allow surgeons to conduct procedures fare less invasively than in the past, but up till now, no surgical adhesive has been visible when using medical imaging techniques such as fluoroscopy, ultrasound, or computed tomography. Now, researchers at the Center for Nanoparticle Research, working with doctors from the Seoul National University Hospital have developed a new medical adhesive that not only forms strong, flexible bonds, but can be monitored using these techniques.

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In preclinical research, the adhesive was able to repair a punctured liver, and bonds remained intact when the adhesive was used on organs that move as they function such as lungs and limbs.

It consists of nanoparticles covered in silica and containing radiopaque tantalum oxide. The silica provides the bonding properties, while the tantalum oxide allows monitoring through ultrasound and CT scans. The silica absorbs into tissue surfaces forming a strong, flexible bond. Researchers say that the adhesive could prove useful in surgeries such as portal vein angioplasty, liver cancer surgeries, and liver biopsies. In addition, there were no adverse side-effects in a 56-day period following procedures conducted on laboratory animals subjected to test procedures.